MS170
Code | Size | Price |
---|
TAR-T39928-5mg | 5mg | £870.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
MS170 is a potent and selective PROTAC AKT degrader. MS170 depletes cellular total AKT (T-AKT) with the DC 50 value of 32 nM. MS170 binds to AKT1, AKT2, and AKT3 with K d s of 1.3 nM, 77 nM, and 6.5 nM, respectively.
CAS:
2376136-61-5
Formula:
0
Molecular Weight:
0
Purity:
0.98
SMILES:
0
References
Yu X, et al. Design, Synthesis, and Evaluation of Potent, Selective, and Bioavailable AKT Kinase Degraders. J Med Chem. 2021;64(24):18054-18081.