CDK6/9-IN-1

TargetMol
Product Code: TAR-T40047
Supplier: TargetMol
CodeSizePrice
TAR-T40047-5mg5mg£850.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

1 / 1

Further Information

Bioactivity:
CDK6/9-IN-1 (compound 66) is an orally active active and dual CDK 6 and CDK 9 inhibitor, with IC 50 values of 40.5 nM and 39.5 nM for CDK6 anmd CDK9, respectively.
CAS:
2414373-55-8
Formula:
0
Molecular Weight:
0
Purity:
0.98
SMILES:
0

References

Yang Wang, et al. Discovery and SARs of 5-Chloro- N4-phenyl- N2-(pyridin-2-yl)pyrimidine-2,4-diamine Derivatives as Oral Available and Dual CDK 6 and 9 Inhibitors With Potent Antitumor Activity. J Med Chem. 2020 Mar 26;63(6):3327-3347.