Eflornithine hydrochloride

TargetMol
Product Code: TAR-T40789
Supplier: TargetMol
CodeSizePrice
TAR-T40789-5mg5mg£850.00
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Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Further Information

Bioactivity:
Eflornithine hydrochloride is a specific, irreversible inhibitor of the enzyme ornithine decarboxylase . Eflornithine is a medication for the treatment of African trypanosomiasis and excessive facial hair growth in women.
CAS:
68278-23-9
Formula:
C6H13ClF2N2O2
Molecular Weight:
218.63
Purity:
0.98
SMILES:
Cl.NCCCC(N)(C(F)F)C(O)=O

References

Lipke DW, et al. Eflornithine alters changes in vascular responsiveness associated with coarctation hypertension. Clin Exp Hypertens. 1997 Apr;19(3):297-312. Burri C, et al. Eflornithine for the treatment of human African trypanosomiasis. Parasitol Res. 2003 Jun;90 Supp 1:S49-52. Balfour JA, et al. Topical eflornithine. Am J Clin Dermatol. 2001;2(3):197-201; discussion 202. Kumar A, et al. A method to improve the efficacy of topical eflornithine hydrochloride cream. Drug Deliv. 2016 Jun;23(5):1495-501.