Methylnaltrexone iodide
| Code | Size | Price |
|---|
| TAR-T40845-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Methylnaltrexone iodide, a quaternary derivative of Naltrexone, is an orally active and selective mu-opioid receptor antagonist, functions as a peripherally acting receptor antagonist in tissues of the gastrointestinal tract. Methylnaltrexone iodide has restricted ability to cross the blood-brain barrier.
CAS:
73232-53-8
Formula:
0
Molecular Weight:
0
Purity:
0.98
SMILES:
0
References
Chandrasekaran A, Tong Z, Li H, et al. Metabolism of intravenous methylnaltrexone in mice, rats, dogs, and humans. Drug Metab Dispos. 2010;38(4):606-616.
Foss JF, Orelind E, Goldberg LI. Effects of methylnaltrexone on morphine-induced cough suppression in guinea pigs. Life Sci. 1996;59(15):PL235-PL238.
Rauck R, et al. Randomized, Double-Blind Trial of Oral Methylnaltrexone for the Treatment of Opioid-Induced Constipation in Patients with Chronic Noncancer Pain. Pain Pract. 2017 Jul;17(6):820-828.