5-Carboxamidotryptamine
| Code | Size | Price |
|---|
| TAR-T40865-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
5-Carboxamidotryptamine (5-CT) is a 5-HT 1A , 5-HT 1B , 5-HT 1D , 5-HT 5A , 5-HT 7 receptor agonist[4] . 5-Carboxamidotryptamine has a K i value of 4.6 nM for cloned human 5-HT 5A receptor. 5-Carboxamidotryptamine causes a dose-dependent reduction in rectal temperature of mice[4] .
CAS:
74885-09-9
Formula:
0
Molecular Weight:
0
Purity:
0.98
SMILES:
0
References
Saxena PR, et al. From serotonin receptor classification to the antimigraine drug sumatriptan. Cephalalgia. 1992 Aug;12(4):187-96.
Hurley PT, et al. Functional coupling of a recombinant human 5-HT5A receptor to G-proteins in HEK-293 cells. Br J Pharmacol. 1998 Jul;124(6):1238-44.
Connor HE, et al. 5-Carboxamidotryptamine is a selective agonist at 5-hydroxytryptamine receptors mediating vasodilatation and tachycardia in anaesthetized cats. Br J Pharmacol. 1986 Feb;87(2):417-26.
Guscott MR, Egan E, Cook GP, Stanton JA, Beer MS, Rosahl TW, Hartmann S, Kulagowski J, et al. The hypothermic effect of 5-CT in mice is mediated through the 5-HT7 receptor. Neuropharmacology. 2003 Jun;44(8):1031-7.
Saxena PR,et al. Characterization of 5-hydroxytryptamine receptors in the cranial vasculature. Cephalalgia. 1989;9 Suppl 9:15-22.