Calmodulin antagonist-1
Code | Size | Price |
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TAR-T40895-100mg | 100mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T40895-50mg | 50mg | Enquire | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
Calmodulin antagonist-1 (W-7) is a calmodulin (CaM) antagonist. Calmodulin antagonist-1 inhibits calmodulin-activated Ca 2+ -phosphodiesterase (PDE) (IC 50 =28 μM). Calmodulin antagonist-1 also inhibits trypsin-treated Ca 2+ -PDE (IC 50 =375 μM) in a competitive fashion with respect to cyclic GMP and the K i value is 300 μM.
CAS:
78957-84-3
Formula:
0
Molecular Weight:
0
Purity:
0.98
SMILES:
0
References
Itoh H, et al. Direct interaction of calmodulin antagonists with Ca2+/calmodulin-dependent cyclic nucleotide phosphodiesterase. J Biochem. 1984;96(6):1721-1726.