Volasertib trihydrochloride
Code | Size | Price |
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TAR-T41100-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
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Further Information
Bioactivity:
Volasertib (BI 6727) trihydrochloride is an orally active, highly potent and ATP-competitive Polo-like kinase 1 (PLK1) inhibitor with an IC 50 of 0.87 nM. Volasertib trihydrochloride inhibits PLK2 and PLK3 with IC 50 s of 5 and 56 nM, respectively. Volasertib trihydrochloride induces mitotic arrest and apoptosis . Volasertib trihydrochloride, a dihydropteridinone derivative, shows marked antitumor activity in multiple cancer models.
CAS:
946161-17-7
Formula:
0
Molecular Weight:
0
Purity:
0.98
SMILES:
0