NB-caged Tyrosine hydrochloride

TargetMol
Product Code: TAR-T41208
Supplier: TargetMol
CodeSizePrice
TAR-T41208-5mg5mg£850.00
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Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
NB-caged Tyrosine hydrochloride is a L-Tyrosine caged with photosensitiveortho-nitrobenzyl side chain. Rapidly releases tyrosine when photolyzed (300-350 nm excitation). Is readily incorporated intoE.coliproteins via inclusion in growth media.
CAS:
207727-86-4
Formula:
C16H17ClN2O5
Molecular Weight:
352.77
Purity:
0.98
SMILES:
Cl.N[C@@H](Cc1ccc(OCc2ccccc2[N+]([O-])=O)cc1)C(O)=O

References

Monk et al (2017) Rapid and inexpensive evaluation of nonstandard amino acid incorporation in Escherichia coli. ACS.Synth.Biol. 6 45 PMID: 27648665 Miller et al (1998) Flash decaging of tyrosine sidechains in an ion channel. Neuron. 20 619 PMID: 9581754 Wang et al (2019) Time-resolved protein activation by proximal decaging in living systems. Nature 569 509 PMID: 31068699