Estramustine phosphate
| Code | Size | Price |
|---|
| TAR-T4451L-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T4451L-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T4451L-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Estramustine phosphate can be used to treat prostatic neoplasms; also has radiation protective properties.
CAS:
4891-15-0
Formula:
C23H32Cl2NO6P
Molecular Weight:
520.38
Purity:
0.98
SMILES:
[H][C@@]12CC[C@H](OP(O)(O)=O)[C@@]1(C)CC[C@]1([H])c3ccc(OC(=O)N(CCCl)CCCl)cc3CC[C@@]21[H]
References
Matsumoto K, Tanaka N, Hayakawa N, Ezaki T, Suzuki K, Maeda T, Ninomiya A, Nakamura S. Efficacy of estramustine phosphate sodium hydrate (EMP) monotherapy in castration-resistant prostate cancer patients: report of 102 cases and review of literature. Med Oncol. 2013 Dec;30(4):717. doi: 10.1007/s12032-013-0717-2. Epub 2013 Sep 5. PubMed PMID: 24005812.
Hayakawa N, Matsumoto K, Sato A, Sakamoto H, Ezaki T, Maeda T, Ninomiya A, Nakamura S. Efficacy of tegafur-uracil (UFT) administration in castration-resistant prostate cancer patients with a history of both alternative antiandrogen therapy and estramustine phosphate sodium hydrate therapy. Int Urol Nephrol. 2014 Jun;46(6):1123-9. doi: 10.1007/s11255-013-0634-5. Epub 2013 Dec 20. PubMed PMID: 24356920.
Petrioli R, Roviello G, Fiaschi AI, Laera L, Bianco V, Ponchietti R, Barbanti G, Francini E. Low-Dose Estramustine Phosphate and Concomitant Low-Dose Acetylsalicylic Acid in Heavily Pretreated Patients With Advanced Castration-Resistant Prostate Cancer. Clin Genitourin Cancer. 2015 Oct;13(5):441-6. doi: 10.1016/j.clgc.2015.03.004. Epub 2015 Mar 26. PubMed PMID: 25920994.
Aurilio G, Graffeo R, Bagnardi V, Nol? F, Adamoli L, Pagani O, Gallerani E, Ferrari B, Pruneri G, Goldhirsch A. Estramustine phosphate sodium in heavily pretreated patients with metastatic breast cancer: a retrospective consecutive case series. Int J Clin Oncol. 2015 Feb;20(1):90-4. doi: 10.1007/s10147-014-0694-2. Epub 2014 Apr 12. PubMed PMID: 24722887.