Perospirone
Code | Size | Price |
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TAR-T4576-5mg | 5mg | £119.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T4576-1mL | 1 mL * 10 mM (in DMSO) | £124.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T4576-10mg | 10mg | £152.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T4576-25mg | 25mg | £223.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T4576-50mg | 50mg | £346.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T4576-100mg | 100mg | £542.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
Perospirone is an antagonist of serotonin 5HT2A receptors and dopamine D2 receptors. It also displays affinity towards 5HT1A receptors as a partial agonist.
CAS:
150915-41-6
Formula:
C23H30N4O2S
Molecular Weight:
426.58
Pathway:
Neuroscience; GPCR/G Protein
Purity:
0.9945
SMILES:
[H][C@@]12CCCC[C@]1([H])C(=O)N(CCCCN1CCN(CC1)c1nsc3ccccc13)C2=O
Target:
Dopamine Receptor; 5-HT Receptor
References
Matsushita M, et al. Perospirone, a novel antipsychotic drug, inhibits marble-burying behavior via 5-HT1A receptor in mice: implications for obsessive-compulsive disorder.[J]. Journal of Pharmacological Sciences, 2005, 99(2):154-159.
Ishibashi T, Ohno Y. Perospirone hydrochloride: the novel atypical antipsychotic agent with high affinities for 5-HT2, D2 and 5-HT1A receptors[J]. Biogenic Amines, 2004, 18(3):307-317.
Zhou Y G, et al. Effect of the novel antipsychotic drug perospirone on P-glycoprotein function and expression in Caco-2 cells[J]. European Journal of Clinical Pharmacology, 2008, 64(7):697-703.
Murata Y, et al. DNA Methylation Profiling in a Neuroblastoma Cell Line Exposed to the Antipsychotic Perospirone[J]. Pharmacopsychiatry, 2018.