TargetMol

Cridanimod

Product Code:
 
TAR-T5317
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T5317-5mg5mg£119.00
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TAR-T5317-1mL1 mL * 10 mM (in DMSO)£124.00
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TAR-T5317-10mg10mg£152.00
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TAR-T5317-25mg25mg£215.00
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TAR-T5317-50mg50mg£302.00
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TAR-T5317-100mg100mg£464.00
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Quantity:
TAR-T5317-500mg500mg£946.00
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This product comes from: United States.
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Further Information

Bioactivity:
Cridanimod (10-carboxymethyl-9-acridanone, CMA) is a potent STING agonist that directly binds to STING and triggers a strong antiviral response through the TBK1/IRF3 route.
CAS:
38609-97-1
Formula:
C15H11NO3
Molecular Weight:
253.257
Pathway:
; Immunology/Inflammation
Purity:
0.9996
SMILES:
OC(=O)Cn1c2ccccc2c(=O)c2ccccc12
Target:
Progesterone Receptor; STING; IFNAR

References

Zhang H, et al. Rat and human STINGs profile similarly towards anticancer/antiviral compounds. Sci Rep. 2015 Dec 16;5:18035. Cavlar T, et al. Species-specific detection of the antiviral small-molecule compound CMA by STING. EMBO J. 2013 May 15;32(10):1440-50.