TargetMol

5,7-Dihydroxychromone

Product Code:
 
TAR-T5S1805
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T5S1805-1mg1mg£104.00
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TAR-T5S1805-5mg5mg£145.00
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TAR-T5S1805-1mL1 mL * 10 mM (in DMSO)£167.00
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TAR-T5S1805-10mg10mg£177.00
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TAR-T5S1805-25mg25mg£249.00
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TAR-T5S1805-50mg50mg£334.00
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TAR-T5S1805-100mg100mg£462.00
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TAR-T5S1805-500mg500mg£946.00
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Further Information

Bioactivity:
1. 5, 7-Dihydroxychromone isolated from DME is one of the active compounds that may contribute to regulate blood glucose levels. 2. 5, 7-Dihydroxychromone exerts neuroprotective effect against 6-OHDA-induced oxidative stress and apoptosis by activating Nrf2/ARE signal . 3. 5, 7-Dihydroxychromone induces the translocation of Nrf2 to the nucleus and increases Nrf2/ARE binding activity which results in the up-regulation of the expression of Nrf2-dependent antioxidant genes, including HO-1, NQO1, and GCLc.
CAS:
31721-94-5
Formula:
C9H6O4
Molecular Weight:
178.143
Pathway:
Apoptosis; Proteases/Proteasome; ; Immunology/Inflammation; Microbiology/Virology; DNA Damage/DNA Repair; Chromatin/Epigenetic
Purity:
0.9973
SMILES:
Oc1cc(O)c2c(c1)occc2=O
Target:
Virus Protease; PARP; Caspase; Nrf2

References

Kim D W , Lee K T , Kwon J , et al. Neuroprotection against 6-OHDA-induced oxidative stress and apoptosis in SH-SY5Y cells by 5,7-Dihydroxychromone: Activation of the Nrf2/ARE pathway[J]. Life Sciences, 2015, 130:25-30.