9-Methoxycamptothecin
| Code | Size | Price |
|---|
| TAR-T5S1952-1mL | 1 mL * 10 mM (in DMSO) | £107.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T5S1952-25mg | 25mg | £111.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
9-Methoxycamptothecin (MCPT) has antitumour activities through topoisomerase inhibition.
CAS:
39026-92-1
Formula:
C21H18N2O5
Molecular Weight:
378.384
Pathway:
DNA Damage/DNA Repair; Apoptosis
Purity:
0.98
SMILES:
CC[C@@]1(O)C(=O)OCc2c1cc1-c3nc4cccc(OC)c4cc3Cn1c2=O
Target:
Apoptosis; Topoisomerase
References
Liao N , Zhang P , Ao M , et al. 9-Methoxycamptothecin from Nothapodytes foetida Induces Apoptosis in Murine Sarcoma S180 Cells[J]. Zeitschrift f?r Naturforschung C, 2011, 66(9-10):471---476.
Wang H , Ao M , Wu J , et al. TNF? and Fas/FasL pathways are involved in 9-Methoxycamptothecin-induced apoptosis in cancer cells with oxidative stress and G2/M cell cycle arrest[J]. Food and Chemical Toxicology, 2013, 55(Complete):396-410.