TargetMol

Deoxyshikonin

Product Code:
 
TAR-T5S2347
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T5S2347-1mL1 mL * 10 mM (in DMSO)£151.00
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TAR-T5S2347-10mg10mg£175.00
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Further Information

Bioactivity:
1. Deoxyshikonin may be a new drug candidate for wound healing and treatment of lymphatic diseases. 2. Deoxyshikonin enhances the ability of human dermal lymphatic microvascular endothelial cells (HMVEC-dLy) to undergo time-dependent in vitro cord formation. 3. Deoxyshikonin and dodecyl gallate show significantly synergic antimicrobial activity with penicillin in vivo and in vitro, and can effectively reduce nasopharyngeal and lung colonization caused by different penicillin-resistant pneumococcal serotypes.
CAS:
43043-74-9
Formula:
C16H16O4
Molecular Weight:
272.3
Pathway:
Chromatin/Epigenetic; ; Metabolism; Microbiology/Virology
Purity:
0.9958
SMILES:
CC(C)=CCCC1=CC(=O)c2c(O)ccc(O)c2C1=O
Target:
HIF/HIF Prolyl-Hydroxylase; Antibacterial

References

Prangsaengtong O , Park J Y , Inujima A , et al. Enhancement of Lymphangiogenesis In Vitro via the Regulations of HIF-1 Expression and Nuclear Translocation by Deoxyshikonin[J]. Evidence-Based Complementary and Alternative Medicine, 2013, 2013:1-11. Zhang Y, Gao J, Xu Y, et al. Investigation of cytochrome P450 inhibitory properties of deoxyshikonin, a bioactive compound from Lithospermum erythrorhizon Sieb. et Z ucc. Phytotherapy Research. 2022