EN106

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TargetMol
Product Code: TAR-T60096
Supplier: TargetMol
CodeSizePrice
TAR-T60096-5mg5mg£108.00
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TAR-T60096-10mg10mg£130.00
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Quantity:
TAR-T60096-25mg25mg£189.00
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TAR-T60096-50mg50mg£257.00
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Quantity:
TAR-T60096-100mg100mg£371.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
EN106 is a potent inhibitor of FEMIB and is a cysteine-reactive covalent ligand. EN106 disrupts recognition of the key reductive stress substrate of FEM1B, FNIP1.
CAS:
757192-67-9
Formula:
C13H13ClN2O3
Molecular Weight:
280.71
Purity:
0.98
SMILES:
ClCC(=O)N(CCC#N)c1ccc2OCCOc2c1

References

Henning NJ, et al. Discovery of a Covalent FEM1B Recruiter for Targeted Protein Degradation Applications. J Am Chem Soc. 2022;144(2):701-708.