GW 441756

TargetMol
Product Code: TAR-T6052
Supplier: TargetMol
CodeSizePrice
TAR-T6052-5mg5mg£111.00
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TAR-T6052-1mL1 mL * 10 mM (in DMSO)£116.00
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Quantity:
TAR-T6052-10mg10mg£135.00
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Quantity:
TAR-T6052-25mg25mg£195.00
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TAR-T6052-50mg50mg£261.00
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TAR-T6052-100mg100mg£359.00
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TAR-T6052-500mg500mg£752.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
GW 441756 is a specific Tropomyosin-related kinase A (TrkA) inhibitor with an IC50 value of 2 nM.
CAS:
504433-23-2
Formula:
C17H13N3O
Molecular Weight:
275.311
Pathway:
Cell Cycle/Checkpoint; Apoptosis; MAPK; Tyrosine Kinase/Adaptors
Purity:
0.998
SMILES:
Cn1cc(C=C2C(=O)Nc3cccnc23)c2ccccc12
Target:
Apoptosis; Raf; Trk receptor; CDK

References

Wood ER, et al. Bioorg Med Chem Lett, 2004, 14(4), 953-957. Jung EJ, et al. Mol Cells, 2008, 26(1), 12-17. Eun Joo Jung, et al. Exp Mol Med, 2008, 40(3), 276?285.