TargetMol

Abiraterone

Product Code:
 
TAR-T6216
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T6216-5mg5mg£98.00
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Quantity:
TAR-T6216-10mg10mg£113.00
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TAR-T6216-25mg25mg£119.00
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TAR-T6216-50mg50mg£124.00
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Quantity:
TAR-T6216-100mg100mg£136.00
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Quantity:
TAR-T6216-200mg200mg£152.00
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Quantity:
TAR-T6216-500mg500mg£167.00
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Quantity:
TAR-T6216-1g1g£191.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
Abiraterone (CB-7598) is an effective steroidal cytochrome P450 17alpha-hydroxylase-17, 20-lyase (CYP17) inhibitor (IC50: 4 nM).
CAS:
154229-19-3
Formula:
C24H31NO
Molecular Weight:
349.518
Pathway:
Metabolism
Purity:
0.9987
SMILES:
C[C@]12CC[C@H]3[C@@H](CC=C4C[C@@H](O)CC[C@]34C)[C@@H]1CC=C2c1cccnc1
Target:
P45

References

Ghoochani A, Hsu E C, Aslan M, et al. Ferroptosis inducers are a novel therapeutic approach for advanced prostate cancer[J]. Cancer research. 2021 Richards J, et al. Cancer Res. 2012, 72(9), 2176-2182. Attard G, et al. J Clin Oncol. 2008, 26(28), 4563-4571. Hu Q, et al. J Med Chem. 2010, 53(15), 5749-5758. Bruno RD, et al. Steroids. 2011, 76(12), 1268-1279. Duc I, et al. J Steroid Biochem Mol Biol. 2003, 84(5), 537-542. Ghoochani A, Hsu E C, Aslan M, et al. Ferroptosis inducers are a novel therapeutic approach for advanced prostate cancer. Cancer research. 2021 Mar 15;81(6):1583-1594. doi: 10.1158/0008-5472.CAN-20-3477. Epub 2021 Jan 22.