AT7867

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TargetMol
Product Code: TAR-T6304
Supplier: TargetMol
CodeSizePrice
TAR-T6304-1mg1mg£106.00
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TAR-T6304-2mg2mg£119.00
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TAR-T6304-1mL1 mL * 10 mM (in DMSO)£149.00
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TAR-T6304-5mg5mg£149.00
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TAR-T6304-10mg10mg£175.00
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TAR-T6304-25mg25mg£254.00
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TAR-T6304-50mg50mg£367.00
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TAR-T6304-100mg100mg£511.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
AT7867 is a potent ATP-competitive inhibitor of Akt1/2/3 and p70S6K/PKA with IC50 of 32 nM/17 nM/47 nM and 85 nM/20 nM, respectively; little activity outside the AGC kinase family.
CAS:
857531-00-1
Formula:
C20H20ClN3
Molecular Weight:
337.85
Pathway:
Cytoskeletal Signaling; Tyrosine Kinase/Adaptors; MAPK; PI3K/Akt/mTOR signaling
Purity:
0.9965
SMILES:
Clc1ccc(cc1)C1(CCNCC1)c1ccc(cc1)-c1cn[nH]c1
Target:
Akt; PKA; S6 Kinase

References

Grimshaw KM, Mol Cancer Ther, 2010, 9(5), 1100-1110.