PCI-34051

TargetMol
Product Code: TAR-T6325
Supplier: TargetMol
CodeSizePrice
TAR-T6325-5mg5mg£115.00
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Quantity:
TAR-T6325-1mL1 mL * 10 mM (in DMSO)£119.00
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Quantity:
TAR-T6325-10mg10mg£148.00
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Quantity:
TAR-T6325-25mg25mg£227.00
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Quantity:
TAR-T6325-50mg50mg£369.00
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Quantity:
TAR-T6325-100mg100mg£550.00
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Quantity:
TAR-T6325-500mg500mg£1,083.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
PCI-34051 is an effective and selective HDAC8 inhibitor (IC50: 10 nM).
CAS:
950762-95-5
Formula:
C17H16N2O3
Molecular Weight:
296.326
Pathway:
Apoptosis; DNA Damage/DNA Repair; Chromatin/Epigenetic
Purity:
0.9914
SMILES:
COc1ccc(Cn2ccc3ccc(cc23)C(=O)NO)cc1
Target:
Apoptosis; HDAC

References

Ren Y, et al. Therapeutic effects of histone deacetylase inhibitors in a murine asthma model. Inflamm Res. 2016 Dec;65(12):1995-12008. Balasubramanian S, et al. Leukemia. 2008, 22(5), 1026-1034.