TargetMol

Anacardic Acid

Product Code:
 
TAR-T6389
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T6389-5mg5mg£107.00
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Quantity:
TAR-T6389-1mL1 mL * 10 mM (in DMSO)£111.00
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TAR-T6389-10mg10mg£128.00
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TAR-T6389-25mg25mg£186.00
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TAR-T6389-50mg50mg£244.00
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Quantity:
TAR-T6389-100mg100mg£332.00
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Further Information

Bioactivity:
Anacardic Acid is an effective inhibitor of p300 and p300/CBP-associated factor histone acetyltranferases. It also has antimicrobial activity, antibacterial activity, and inhibits prostaglandin synthase, lipoxygenase, and tyrosinase.
CAS:
16611-84-0
Formula:
C22H36O3
Molecular Weight:
348.527
Pathway:
; Chromatin/Epigenetic; Microbiology/Virology
Purity:
0.9972
SMILES:
CCCCCCCCCCCCCCCc1cccc(O)c1C(O)=O
Target:
Epigenetic Reader Domain; Histone Acetyltransferase; Antibacterial

References

Hemshekhar M,etal.Emerging roles of anacardic acid and its derivatives: a pharmacological overview.Basic Clin Pharmacol Toxicol. 2012 Feb;110(2):122-32. Yan H, Liu Z, Yan G, et al. A robust high-throughput fluorescence polarization assay for rapid screening of SARS-CoV-2 papain-like protease inhibitors. Virology. 2022 Radde BN, et al.J Cell Biochem. 2016 Mar 17. Peng C,etal.Inhibition of histone H3K9 acetylation by anacardic acid can correct the over-expression of Gata4 in the hearts of fetal mice exposed to alcohol during pregnancy.PLoS One. 2014 Aug 7;9(8):e104135. Yao K, et al.Int J Clin Exp Pathol. 2015 Dec 1;8(12):15926-32. eCollection 2015. Peng C, et al. Phenylephrine-induced cardiac hypertrophy is attenuated by a histone acetylase inhibitor anacardic acid in mice. Mol Biosyst. 2017 Mar 28;13(4):714-724.