Clinofibrate

TargetMol
Product Code: TAR-T6450
Supplier: TargetMol
CodeSizePrice
TAR-T6450-5mg5mg£102.00
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Quantity:
TAR-T6450-1mL1 mL * 10 mM (in DMSO)£103.00
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Quantity:
TAR-T6450-10mg10mg£115.00
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Quantity:
TAR-T6450-25mg25mg£161.00
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Quantity:
TAR-T6450-50mg50mg£217.00
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Quantity:
TAR-T6450-100mg100mg£303.00
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Quantity:
TAR-T6450-200mg200mg£414.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
Clinofibrate?IC50 of 0.47 mM?, a lipid-lowering agent, inhibits hydroxymethylglutaryl coenzyme A reductase (HMGCR). It is utilized to control high cholesterol and triacylglyceride levels in the blood.
CAS:
30299-08-2
Formula:
C28H36O6
Molecular Weight:
468.59
Pathway:
Metabolism; Autophagy
Purity:
0.9984
SMILES:
CCC(C)(Oc1ccc(cc1)C1(CCCCC1)c1ccc(OC(C)(CC)C(O)=O)cc1)C(O)=O
Target:
HMG-CoA Reductase; Autophagy

References

Shirai K, et al, Artery, 1983, 12(3), 145-155. Matsuura K, et al, J Pharmacol Exp Ther, 1998, 285(3), 1096-1103.