GW 5074

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TargetMol
Product Code: TAR-T6525
Supplier: TargetMol
CodeSizePrice
TAR-T6525-2mg2mg£99.00
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TAR-T6525-5mg5mg£114.00
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TAR-T6525-1mL1 mL * 10 mM (in DMSO)£124.00
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Quantity:
TAR-T6525-10mg10mg£143.00
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Quantity:
TAR-T6525-25mg25mg£180.00
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Quantity:
TAR-T6525-50mg50mg£208.00
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TAR-T6525-100mg100mg£237.00
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TAR-T6525-200mg200mg£309.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
GW5074(IC50=9 nM) is an effective and specific c-Raf inhibitor. It has no effect on the activities of JNK1/2/3, MEK1, MKK6/7, CDK1/2, c-Src, p38 MAP, VEGFR2 or c-Fms.
CAS:
220904-83-6
Formula:
C15H8Br2INO2
Molecular Weight:
520.946
Pathway:
Apoptosis; MAPK
Purity:
0.973
SMILES:
Oc1c(Br)cc(C=C2/C(=O)Nc3ccc(I)cc23)cc1Br
Target:
Apoptosis; Raf

References

Chin PC, et al. J Neurochem, 2004, 90(3), 595-608. Lei Y, et al. Respir Res, 2008, 9(1), 71. Yue X, et al. Eur J Pharmacol, 2006, 540(1-3), 57-59.