NMS-E973

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TargetMol
Product Code: TAR-T6609
Supplier: TargetMol
CodeSizePrice
TAR-T6609-1mg1mg£103.00
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TAR-T6609-5mg5mg£148.00
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TAR-T6609-1mL1 mL * 10 mM (in DMSO)£156.00
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TAR-T6609-10mg10mg£201.00
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TAR-T6609-25mg25mg£349.00
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TAR-T6609-50mg50mg£523.00
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TAR-T6609-100mg100mg£723.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
NMS-E973 is a potent and selective Hsp90 inhibitor with DC50 of <10 nM for Hsp90 binding, no activiy against a panel of 52 diverse protein kinases.
CAS:
1253584-84-7
Formula:
C22H22N4O7
Molecular Weight:
454.439
Pathway:
Cytoskeletal Signaling; Metabolism
Purity:
0.98
SMILES:
CN1CCC(CC1)NC(=O)c1cc(on1)-c1c(O)cc(O)cc1Oc1ccc(cc1)[N+]([O-])=O
Target:
HSP

References

Brasca MG, et al. Bioorg Med Chem. 2013, 21(22), 7047-7063. Fogliatto G, et al. Clin Cancer Res. 2013, 19(13), 3520-3532.