Vatalanib dihydrochloride

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TargetMol
Product Code: TAR-T6720
Supplier: TargetMol
CodeSizePrice
TAR-T6720-5mg5mg£95.00
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TAR-T6720-1mL1 mL * 10 mM (in DMSO)£107.00
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Quantity:
TAR-T6720-10mg10mg£108.00
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Quantity:
TAR-T6720-25mg25mg£121.00
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Quantity:
TAR-T6720-50mg50mg£125.00
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Quantity:
TAR-T6720-100mg100mg£148.00
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Quantity:
TAR-T6720-200mg200mg£201.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
Vatalanib (PTK787) (IC50=37 nM) is an inhibitor of VEGFR2/KDR. It exhibits less effective against VEGFR1/Flt-1 and 18-fold against VEGFR3/Flt-4.
CAS:
212141-51-0
Formula:
C20H17Cl3N4
Molecular Weight:
419.73
Pathway:
Apoptosis; Angiogenesis; Tyrosine Kinase/Adaptors
Purity:
0.9978
SMILES:
Cl.Cl.Clc1ccc(Nc2nnc(Cc3ccncc3)c3ccccc23)cc1
Target:
Apoptosis; VEGFR; PDGFR

References

Murakami M, et al. Ann Surg Oncol. 2011, 18(2), 589-596. Wood JM, et al. Cancer Res. 2000, 60(8), 2178-2189.