WZ8040

TargetMol
Product Code: TAR-T6734
Supplier: TargetMol
CodeSizePrice
TAR-T6734-1mg1mg£103.00
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TAR-T6734-5mg5mg£147.00
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TAR-T6734-1mL1 mL * 10 mM (in DMSO)£148.00
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TAR-T6734-10mg10mg£193.00
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TAR-T6734-25mg25mg£279.00
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TAR-T6734-50mg50mg£380.00
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TAR-T6734-100mg100mg£526.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Further Information

Bioactivity:
WZ8040 is a novel mutant-selective irreversible EGFRT790M inhibitor, does not inhibit ERBB2 phosphorylation (T798I).
CAS:
1214265-57-2
Formula:
C24H25ClN6OS
Molecular Weight:
481.02
Pathway:
Tyrosine Kinase/Adaptors; JAK/STAT signaling; Angiogenesis
Purity:
0.98
SMILES:
CN1CCN(CC1)c1ccc(Nc2ncc(Cl)c(Sc3cccc(NC(=O)C=C)c3)n2)cc1
Target:
EGFR

References

Zhou W, et al. Nature, 2009, 462(7276), 1070-1074.