(E/Z)-4-Hydroxytamoxifen

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TargetMol
Product Code: TAR-T6743
Supplier: TargetMol
CodeSizePrice
TAR-T6743-5mg5mg£108.00
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TAR-T6743-1mL1 mL * 10 mM (in DMSO)£112.00
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Quantity:
TAR-T6743-10mg10mg£128.00
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Quantity:
TAR-T6743-25mg25mg£174.00
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Quantity:
TAR-T6743-50mg50mg£242.00
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Quantity:
TAR-T6743-100mg100mg£334.00
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Quantity:
TAR-T6743-200mg200mg£466.00
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TAR-T6743-500mg500mg£704.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
4-Hydroxytamoxifen is the active metabolite of tamoxifen and a selective estrogen receptor (ER) modulator that is widely used in the therapeutic and chemopreventive treatment of breast cancer.
CAS:
68392-35-8
Formula:
C26H29NO2
Molecular Weight:
387.523
Pathway:
Endocrinology/Hormones
Purity:
0.991
SMILES:
CCC(=C(c1ccc(O)cc1)c1ccc(OCCN(C)C)cc1)c1ccccc1
Target:
Estrogen Receptor/ERR; Estrogen/progestogen Receptor

References

Wang D, Yin Z, Wang H, et al.The super elongation complex drives transcriptional addiction in MYCN-amplified neuroblastoma.Science Advances.2023, 9(13): eadf0005. Beland FA, et al. Carcinogenesis. 1999, 20(3):471-477. Asp ML, et al. PLoS One. 2013, 8(10):e78768.