CFSE

TargetMol
Product Code: TAR-T6802
Supplier: TargetMol
CodeSizePrice
TAR-T6802-5mg5mg£112.00
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Quantity:
TAR-T6802-1mL1 mL * 10 mM (in DMSO)£136.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T6802-10mg10mg£139.00
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Quantity:
TAR-T6802-25mg25mg£180.00
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Quantity:
TAR-T6802-50mg50mg£230.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T6802-100mg100mg£309.00
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Quantity:
TAR-T6802-200mg200mg£438.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

1 / 1

Further Information

Bioactivity:
Carboxyfluorescein succinimidyl ester (CFSE) is a fluorescent cell staining dye. CFSE is cell permeable and covalently couples, via its succinimidyl group, to intracellular molecules, notably, to intracellular lysine residues and other amine sources.
CAS:
150347-59-4
Formula:
C58H38N2O22
Molecular Weight:
1114.934
Purity:
0.9898
SMILES:
CC(=O)Oc1ccc2c(Oc3cc(OC(C)=O)ccc3C22OC(=O)c3cc(ccc23)C(=O)ON2C(=O)CCC2=O)c1.CC(=O)Oc1ccc2c(Oc3cc(OC(C)=O)ccc3C22OC(=O)c3ccc(cc23)C(=O)ON2C(=O)CCC2=O)c1

References

Wang XQ, et al. Acta Biochim Biophys Sin (Shanghai). 2005, 37(6):379-85. Xiao C, Su J, Zhang C, et al. Effectiveness of Booster Doses of the SARS-CoV-2 Inactivated Vaccine KCONVAC against the Mutant Strains. Viruses. 2022, 14(9): 2016. Deng J, Pan J, Qiu M, et al. Identification of HLA-A2 restricted CD8+ T cell epitopes in SARS-CoV-2 structural proteins. Journal of Leukocyte Biology. 2021 Liao Y, Huang J, Liu P, et al. Downregulation of LNMAS orchestrates partial EMT and immune escape from macrophage phagocytosis to promote lymph node metastasis of cervical cancer. Oncogene. 2022: 1-13. Xiao C, Mao L, Wang Z, et al. SARS-CoV-2 variant B. 1.1. 7 caused HLA-A2+ CD8+ T cell epitope mutations for impaired cellular immune response. Iscience. 2022 Mar 18;25(3):103934. doi: 10.1016/j.isci.2022.103934. Epub 2022 Feb 17. Jablonski S, Mou H, Otsuka Y, et al. Identification of Potent Small Molecule Inhibitors of SARS-CoV-2 Entry. SLAS Discovery. 2021 Graziano M, et al. Exp Cell Res. 1998, 240(1):75-85. Li M, Qin M, Song G, et al. A biomimetic antitumor nanovaccine based on biocompatible calcium pyrophosphate and tumor cell membrane antigens[J]. Asian Journal of Pharmaceutical Sciences. 2020 Guo E, Xiao R, Wu Y, et al. WEE1 inhibition induces anti-tumor immunity by activating ERV and the dsRNA pathway. Journal of Experimental Medicine. 2021, 219(1): e20210789. Xiao C, Mao L, Wang Z, et al. SARS-CoV-2 variant B. 1.1. 7 caused HLA-A2+ CD8+ T cell epitope mutations for impaired cellular immune response[J]. bioRxiv. 2021 Zhao G, Tong Y, Xu J, et al.Jing-Fang powder ethyl acetate extracts attenuate atopic dermatitis by modulating T-cell activity.Molecular Immunology.2023, 160: 133-149. Xiao C, Ren Z, Zhang B, et al.Insufficient epitope-specific T cell clones are responsible for impaired cellular immunity to inactivated SARS-CoV-2 vaccine in older adults.Nature Aging.2023: 1-18. Yang L, Wu J, Mei G, et al.Corydalis Saxicola Bunting Total Alkaloid Eliminates Porphyromonas gingivalis strain 33277 Internalized into Macrophages by Inhibition of TLR2.Microbes and Infection.2023: 105244.