Deguelin
Code | Size | Price |
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TAR-T6817-5mg | 5mg | £106.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T6817-1mL | 1 mL * 10 mM (in DMSO) | £111.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T6817-10mg | 10mg | £131.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T6817-25mg | 25mg | £179.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T6817-50mg | 50mg | £280.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T6817-100mg | 100mg | £422.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
Deguelin is a PI3K/AKT Inhibitor, which is a natural product isolated from plants in the Mundulea sericea family.
CAS:
522-17-8
Formula:
C23H22O6
Molecular Weight:
394.423
Pathway:
Cytoskeletal Signaling; Autophagy; PI3K/Akt/mTOR signaling; Apoptosis
Purity:
0.9826
SMILES:
COc1cc2OC[C@H]3Oc4c(ccc5OC(C)(C)C=Cc45)C(=O)[C@H]3c2cc1OC
Target:
Apoptosis; Akt; PI3K; Autophagy
References
Liu X, Yang J, Yang C, et al. Morphine promotes the?malignant biological behavior of?non-small cell lung cancer cells through?the?MOR/Src/mTOR pathway. Cancer cell International. 2021, 21(1): 1-14
Wang Y, et al. Mol Clin Oncol. 2013, 1(2):215-219.
Bortul R, et al. Br J Haematol. 2005, 129(5):677-86.
Liu X, Yang J, Yang C, et al. Morphine promotes the?malignant biological behavior of non-small cell lung cancer cells through the MOR/Src/mTOR pathway. Cancer Cell International. 2021, 21(1): 1-14
Yan Y, et al. Neoplasia. 2005, 7(12):1053-7.
Kim JH, et al. J Pharmacol Exp Ther. 2008, 324(2):643-7.