EAI045

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TargetMol
Product Code: TAR-T6824
Supplier: TargetMol
CodeSizePrice
TAR-T6824-5mg5mg£99.00
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Quantity:
TAR-T6824-1mL1 mL * 10 mM (in DMSO)£111.00
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Quantity:
TAR-T6824-10mg10mg£114.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T6824-25mg25mg£138.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T6824-50mg50mg£172.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T6824-100mg100mg£237.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
EAI045, an allosteric inhibitor, targets towards drug-resistant EGFR mutants but avoids the wild-type receptor.
CAS:
1942114-09-1
Formula:
C19H14FN3O3S
Molecular Weight:
383.4
Pathway:
Tyrosine Kinase/Adaptors; Angiogenesis; JAK/STAT signaling
Purity:
0.9973
SMILES:
Oc1ccc(F)cc1C(N1Cc2ccccc2C1=O)C(=O)Nc1nccs1
Target:
EGFR

References

Jia Y, et al. Nature. 2016, 534(7605):129-32. Wang S, et al. J Hematol Oncol. 2016, 9(1):59.