ML264

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TargetMol
Product Code: TAR-T6894
Supplier: TargetMol
CodeSizePrice
TAR-T6894-1mg1mg£96.00
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TAR-T6894-1mL1 mL * 10 mM (in DMSO)£124.00
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Quantity:
TAR-T6894-5mg5mg£124.00
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Quantity:
TAR-T6894-10mg10mg£152.00
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Quantity:
TAR-T6894-25mg25mg£238.00
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Quantity:
TAR-T6894-50mg50mg£362.00
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TAR-T6894-100mg100mg£510.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
ML264 is a selective kruppel-like factor 5 (KLF5) inhibitor, which potently Inhibits growth of Colorectal Cancer.
CAS:
1550008-55-3
Formula:
C17H21ClN2O4S
Molecular Weight:
384.88
Pathway:
DNA Damage/DNA Repair; MAPK; Cell Cycle/Checkpoint
Purity:
0.9945
SMILES:
CN(C1CCS(=O)(=O)CC1)C(=O)CNC(=O)C=Cc1cccc(Cl)c1
Target:
DNA/RNA Synthesis; KLF

References

Bialkowska A,et al. Probe Reports from the NIH Molecular Libraries Program. 2010-2011 Oct 31 [updated 2013 Mar 7]. Ruiz de Sabando A, et al. Mol Cancer Ther. 2016, 15(1):72-83. Shen X, Zhang Y, Xu Z, et al. KLF5 inhibition overcomes oxaliplatin resistance in patient-derived colorectal cancer organoids by restoring apoptotic response. Cell Death & Disease. 2022, 13(4): 1-13