NPS-1034

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TargetMol
Product Code: TAR-T6907
Supplier: TargetMol
CodeSizePrice
TAR-T6907-1mg1mg£96.00
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TAR-T6907-5mg5mg£128.00
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TAR-T6907-1mL1 mL * 10 mM (in DMSO)£143.00
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TAR-T6907-10mg10mg£152.00
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TAR-T6907-25mg25mg£237.00
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TAR-T6907-50mg50mg£346.00
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TAR-T6907-100mg100mg£456.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
NPS-1034 is a dual Met/Axl inhibitor with IC50 of 48 nM and 10.3 nM, respectively.
CAS:
1221713-92-3
Formula:
C31H23F2N5O3
Molecular Weight:
551.554
Pathway:
Tyrosine Kinase/Adaptors; Apoptosis
Purity:
0.9786
SMILES:
Cc1c(C(=O)Nc2ccc(Oc3ccnc4[nH]cc(-c5ccccc5)c34)c(F)c2)c(=O)n(-c2ccc(F)cc2)n1C
Target:
Apoptosis; c-Met/HGFR; TAM Receptor

References

Shin JS, et al. Invest New Drugs. 2014, 32(3), 389-399. Rho JK, et al. Cancer Res. 2014, 74(1), 253-262.