Omaveloxolone

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TargetMol
Product Code: TAR-T6919
Supplier: TargetMol
CodeSizePrice
TAR-T6919-1mg1mg£101.00
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TAR-T6919-2mg2mg£114.00
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TAR-T6919-5mg5mg£142.00
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TAR-T6919-1mL1 mL * 10 mM (in DMSO)£158.00
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TAR-T6919-10mg10mg£168.00
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TAR-T6919-25mg25mg£249.00
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TAR-T6919-50mg50mg£369.00
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TAR-T6919-100mg100mg£503.00
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TAR-T6919-500mg500mg£994.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
Omaveloxolone (RTA-408) is a synthetic triterpenoid that activates the cytoprotective transcription factor Nrf2 and inhibits NF-κB signaling. Phase 2.
CAS:
1474034-05-3
Formula:
C33H44F2N2O3
Molecular Weight:
554.723
Pathway:
Apoptosis; ; Immunology/Inflammation
Purity:
0.987
SMILES:
[H][C@@]12CC(C)(C)CC[C@@]1(CC[C@]1(C)[C@]2([H])C(=O)C=C2[C@@]1(C)CC[C@@]1([H])C(C)(C)C(=O)C(=C[C@]21C)C#N)NC(=O)C(C)(F)F
Target:
Apoptosis; Nrf2; STING

References

Reisman SA, et al. Arch Dermatol Res. 2014, 306(5), 447-454. Reisman SA, et al. Radiat Res. 2014, 181(5), 512-520. Probst BL, et al. PLoS One. 2015, 10(4), e20122942. Goldman DC, et al. Radiat Res. 2015, 183(3), 338-344.