TargetMol

Piperlongumine

Product Code:
 
TAR-T6947
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
❮❯

No additional charges, what you see is what you pay! *

CodeSizePrice
TAR-T6947-1mL1 mL * 10 mM (in DMSO)£95.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T6947-10mg10mg£95.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T6947-25mg25mg£111.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T6947-50mg50mg£135.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T6947-100mg100mg£168.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
Prices exclude any Taxes / VAT
How to order with us   Contact us
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: United States.
Typical lead time: 10-14 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • References
  • Show All

Further Information

Bioactivity:
Piperlongumine is a natural alkaloid from Piper longum L. It selectively kills cancer cells and strengthens the level of reactive oxygen species (ROS).
CAS:
20069-09-4
Formula:
C17H19NO5
Molecular Weight:
317.341
Pathway:
Microbiology/Virology; Autophagy; Metabolism; Immunology/Inflammation; NF-κb; MAPK; Cell Cycle/Checkpoint; Apoptosis
Purity:
0.9721
SMILES:
COc1cc(C=CC(=O)N2CCC=CC2=O)cc(OC)c1OC
Target:
Apoptosis; ERK; Ferroptosis; Reactive Oxygen Species; ROS; Antibacterial; Autophagy

References

Bezerra DP, et al. J Appl Toxicol. 2008, 28(5), 599-607. Wu X, e,t al. Piperlongumine inhibits angiotensin II-induced extracellular matrix expression in cardiac fibroblasts. J Cell Biochem. 2018 Dec;119(12):10358-10364 Zou P, et al. Cancer Lett. 2016, 375(1):114-26. Ryu J, et al. Nat Prod Res. 2014, 28(22), 2040-2043. Dhillon H, et al. Toxicol Rep. 2014, 1:309-318. Iwashita M, et al. Eur J Pharmacol. 2007, 570(1-3), 38-42. Qiu C, Shen X, Lu H, et al.Combination therapy with HSP90 inhibitors and piperlongumine promotes ROS-mediated ER stress in colon cancer cells.Cell Death Discovery.2023, 9(1): 375. Kong Y, Liu Y, Li X, et al.Palmitoylation landscapes across human cancers reveal a role of palmitoylation in tumorigenesis.Journal of Translational Medicine.2023, 21(1): 1-19.