PRIMA-1

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TargetMol
Product Code: TAR-T6954
Supplier: TargetMol
CodeSizePrice
TAR-T6954-5mg5mg£108.00
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TAR-T6954-1mL1 mL * 10 mM (in DMSO)£112.00
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Quantity:
TAR-T6954-10mg10mg£124.00
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Quantity:
TAR-T6954-25mg25mg£185.00
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Quantity:
TAR-T6954-50mg50mg£245.00
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Quantity:
TAR-T6954-100mg100mg£381.00
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Quantity:
TAR-T6954-200mg200mg£533.00
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TAR-T6954-500mg500mg£812.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
PRIMA-1 is a mutant p53 reactivator. It induces apoptosis and inhibits growth of human tumors with mutant p53.
CAS:
5608-24-2
Formula:
C9H15NO3
Molecular Weight:
185.223
Pathway:
Apoptosis; Cell Cycle/Checkpoint; ; Autophagy
Purity:
0.98
SMILES:
OCC1(CO)N2CCC(CC2)C1=O
Target:
Apoptosis; Ferroptosis; Autophagy

References

Bykov VJ, et al. Nat Med. 2002, 8(3):282-8. Izetti P, et al. Invest New Drugs. 2014, 32(5):783-94. Lambert JM, et al. Cancer Cell. 2009, 15(5):376-88. Farhadi E, et al. Anticancer Drugs. 2016.