RHPS4
Code | Size | Price |
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TAR-T6967-5mg | 5mg | £102.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T6967-1mL | 1 mL * 10 mM (in DMSO) | £112.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T6967-10mg | 10mg | £122.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T6967-25mg | 25mg | £172.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T6967-50mg | 50mg | £262.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T6967-100mg | 100mg | £389.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
RHPS4 is a potent inhibitor of Telomerase at submicromolar.
CAS:
390362-78-4
Formula:
C23H20F2N2O4S
Molecular Weight:
458.48
Pathway:
Apoptosis; DNA Damage/DNA Repair
Purity:
0.9859
SMILES:
COS([O-])(=O)=O.Cc1cc2n(C)c3ccc(F)cc3c3[n+](C)c4ccc(F)cc4c(c1)c23
Target:
Apoptosis; Telomerase
References
Gao C, Deng J, Anwar N, et al.Molecular crowding promotes the aggregation of parallel structured G-quadruplexes.International Journal of Biological Macromolecules.2023: 124442.
Salvati E, et al. J Clin Invest. 2007, 117(11):3236-47.
Phatak P, et al. Br J Cancer. 2007, 96(8):1223-33.
Wang Z, Deng J, Umer M, et al. RHPS4 shifted the conformation ensemble equilibrium of Tel24 by preferentially stabilizing the (3+ 1) hybrid-2 conformation. RSC Advances. 2022, 12(40): 26011-26015.