Sivelestat

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TargetMol
Product Code: TAR-T6986
Supplier: TargetMol
CodeSizePrice
TAR-T6986-5mg5mg£104.00
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TAR-T6986-10mg10mg£119.00
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TAR-T6986-1mL1 mL * 10 mM (in DMSO)£125.00
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TAR-T6986-25mg25mg£159.00
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TAR-T6986-50mg50mg£239.00
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TAR-T6986-100mg100mg£324.00
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TAR-T6986-200mg200mg£491.00
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TAR-T6986-500mg500mg£743.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

Images

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Documents

Further Information

Bioactivity:
Sivelestat is a potent and selective inhibitor of neutrophil elastase with IC50 of 44 nM.
CAS:
127373-66-4
Formula:
C20H22N2O7S
Molecular Weight:
434.46
Pathway:
; Proteases/Proteasome; Microbiology/Virology
Purity:
0.9952
SMILES:
CC(C)(C)C(=O)Oc1ccc(cc1)S(=O)(=O)Nc1ccccc1C(=O)NCC(O)=O
Target:
SARS-CoV; Serine Protease

References

Hagiwara S, et al. Inflamm Res. 2009, 58(4):198-203. Wada Y, et al. Cancer Science. 2006, 97(10):1037-1043. Araki Y, et al. Dig Dis Sci. 2011, 56(6):1672-81. Huo J, et al. Neuroscience. 2016, 330:171-180. Li G, et al. Int J Mol Med. 2016, 38(3):767-75.