TargetMol

Engeletin

Product Code:
 
TAR-T6S0840
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T6S0840-5mg5mg£103.00
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TAR-T6S0840-1mL1 mL * 10 mM (in DMSO)£107.00
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TAR-T6S0840-10mg10mg£124.00
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TAR-T6S0840-25mg25mg£189.00
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TAR-T6S0840-50mg50mg£262.00
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TAR-T6S0840-100mg100mg£410.00
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Further Information

Bioactivity:
1. Engeletin may serve as a potential anti-inflammatory agent. 2. Engeletin possesses potent inhibition of PGE2 release with IC5 values of 19.6 μg/ml. 3. Engeletin inhibits a recombinant human aldose reductase (IC5 value=1.16 microM).
CAS:
572-31-6
Formula:
C21H22O10
Molecular Weight:
434.397
Pathway:
Endocrinology/Hormones; Metabolism; NF-κb
Purity:
0.9999
SMILES:
C[C@@H]1O[C@@H](O[C@@H]2[C@H](Oc3cc(O)cc(O)c3C2=O)c2ccc(O)cc2)[C@H](O)[C@H](O)[C@H]1O
Target:
NF-κB; Reductase

References

Feng M, Liu L, Wang J, et al.The Molecular Mechanisms Study of Engeletin Suppresses RANKL-Induced Osteoclastogenesis and Inhibits Ovariectomized Murine Model Bone Loss.Journal of Inflammation Research.2023: 2255-2270. Huang H , Cheng Z , Shi H , et al. Isolation and Characterization of Two Flavonoids, Engeletin and Astilbin, from the Leaves of Engelhardia roxburghiana and Their Potential Anti-inflammatory Properties[J]. Journal of Agricultural and Food Chemistry, 2011, 59(9):4562-4569.