Irisflorentin
| Code | Size | Price |
|---|
| TAR-T6S1665-1mL | 1 mL * 10 mM (in DMSO) | £111.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T6S1665-20mg | 20mg | £119.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
1. Irisflorentin blocks apoptosis pathways, by exerting its effects by promoting rpn-3 expression to enhance the activity of proteasomes and down-regulating egl-1 expression. 2. Irisflorentin has anti-inflammatory mechanism in LPS-activated RAW 264.7 macrophages, by reducing the transcriptional and translational levels of inducible nitric oxide synthase (iNOS) as well as the production of NO.
CAS:
41743-73-1
Formula:
C20H18O8
Molecular Weight:
386.356
Pathway:
; Immunology/Inflammation
Purity:
0.986
SMILES:
COc1cc(cc(OC)c1OC)-c1coc2cc3OCOc3c(OC)c2c1=O
Target:
NO Synthase
References
Chen Y M , Liu S P , Lin H L , et al. Irisflorentin improves ?-synuclein accumulation and attenuates 6-OHDA-induced dopaminergic neuron degeneration, implication for Parkinson?s disease therapy[J]. BioMedicine, 2015, 5(1):4.