LM22A-4

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TargetMol
Product Code: TAR-T7568
Supplier: TargetMol
CodeSizePrice
TAR-T7568-5mg5mg£102.00
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TAR-T7568-1mL1 mL * 10 mM (in DMSO)£105.00
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TAR-T7568-10mg10mg£128.00
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TAR-T7568-25mg25mg£195.00
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TAR-T7568-50mg50mg£289.00
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TAR-T7568-100mg100mg£454.00
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TAR-T7568-500mg500mg£914.00
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Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
LM22A-4 is a brain-derived neurotrophic factor (BDNF) mimetic and agonist of the receptor tropomyosin-related kinase B (TrkB; IC50 : 47 nM in a fluorescence anisotropy assay)
CAS:
37988-18-4
Formula:
C15H21N3O6
Molecular Weight:
339.348
Pathway:
Tyrosine Kinase/Adaptors
Purity:
0.98
SMILES:
OCCNC(=O)c1cc(cc(c1)C(=O)NCCO)C(=O)NCCO
Target:
Trk receptor

References

Simmons D A , Belichenko N P , Yang T , et al. A Small Molecule TrkB Ligand Reduces Motor Impairment and Neuropathology in R6/2 and BACHD Mouse Models of Huntington"s Disease[J]. Journal of Neuroscience