Vinflunine
Code | Size | Price |
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TAR-T7594-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
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Further Information
Bioactivity:
Vinflunine is a new vinca alkaloid uniquely fluorinated with the properties of mitotic-arresting and tubulin-interacting activity.
CAS:
162652-95-1
Formula:
C45H54F2N4O8
Molecular Weight:
816.944
Purity:
0.98
SMILES:
[H][C@@]12N3CC[C@@]11c4cc(c(OC)cc4N(C)[C@@]1([H])[C@](O)([C@H](OC(C)=O)[C@]2(CC)C=CC3)C(=O)OC)[C@]1(CC2([H])C[C@H](CN(C2)Cc2c1[nH]c1ccccc21)C(C)(F)F)C(=O)OC
References
Kruczynski A, et al, Eur J Cancer, 2006, 42(16), 2821-2832.
Pourroy B, et al, Mol Pharmacol, 2004, 66(3), 580-591.
Lobert S, et al, Biochemistry, 2000, 39(39), 12053-12062.
Ngan VK, et al, Cancer Res, 2000, 60(18), 5045-5051.
Okauneva T, et al, Mol Cancer Ther, 2003, 2(5), 427-436.