Budipine Hydrochloride
| Code | Size | Price |
|---|
| TAR-T7626L-5mg | 5mg | £850.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T7626L-50mg | 50mg | £1,661.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T7626L-100mg | 100mg | £2,079.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Budipine is a non-dopaminergic antiparkinsonian drug. The primary action of budipine is an indirect dopaminergic effect as shown by facilitation of dopamine (DA) release, inhibition of monoamine oxidase type B (MAO-B) and of DA (re) up-take and stimulation of aromatic L-amino acid decarboxylase (AADC).
CAS:
63661-61-0
Formula:
C21H28ClN
Molecular Weight:
329.91
Purity:
0.98
SMILES:
[Cl-].CC(C)(C)[NH+]1CCC(CC1)(c1ccccc1)c1ccccc1
References
Owen JC, Whitton PS. Effects of amantadine and budipine on antidepressant drug-evoked changes in extracellular dopamine in the frontal cortex of freely moving rats. Brain Res. 2006 Oct 30;1117(1):206-12. PubMed PMID: 16996043.
Reichmann H. Budipine in Parkinson's tremor. J Neurol Sci. 2006 Oct 25;248(1-2):53-5. Review. PubMed PMID: 16784759.
M?ller T, Kuhn W, Przuntek H. Efficacy of budipine and placebo in untreated patients with Parkinson's disease. J Neural Transm (Vienna). 2005 Aug;112(8):1015-23. PubMed PMID: 15583956.
Fisher A, Wang X, Cock HR, Thom M, Patsalos PN, Walker MC. Synergism between topiramate and budipine in refractory status epilepticus in the rat. Epilepsia. 2004 Nov;45(11):1300-7. PubMed PMID: 15509230.