VTP-27999 TFA
Code | Size | Price |
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TAR-T7668-1mg | 1mg | £106.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T7668-5mg | 5mg | £149.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T7668-10mg | 10mg | £201.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T7668-25mg | 25mg | £309.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
TAR-T7668-50mg | 50mg | £495.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. |
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Images
Documents
Further Information
Bioactivity:
VTP-27999 TFA is an inhibitor of Renin (IC50 : 0.47 nM).
CAS:
1013937-63-7
Formula:
C28H42ClF3N4O7
Molecular Weight:
639.11
Pathway:
Endocrinology/Hormones
Purity:
0.9972
SMILES:
OC(=O)C(F)(F)F.CNC(CNC(=O)N1CCCC(C1)C(OCCNC(=O)OC)c1cccc(Cl)c1)CC1CCCOC1
Target:
RAAS
References
Krop M , Lu X , Verdonk K , et al. New Renin Inhibitor VTP-27999 Alters Renin Immunoreactivity and Does Not Unfold Prorenin[J]. Hypertension, 2013, 61(5):1075-1082.
Ishchenko A , Liu Z , Lindblom P , et al. Structure-Based Design Technology Contour and Its Application to the Design of Renin Inhibitors[J]. Journal of Chemical Information and Modeling, 2012, 52(8):2089-2097.