TargetMol

Aminopterin

Product Code:
 
TAR-T7730
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T7730-5mg5mg£103.00
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TAR-T7730-10mg10mg£124.00
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TAR-T7730-25mg25mg£177.00
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TAR-T7730-50mg50mg£257.00
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TAR-T7730-100mg100mg£369.00
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This product comes from: United States.
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Further Information

Bioactivity:
Aminopterin is a synthetic folic acid derivative whose metabolite is a competitive inhibitor of dihydrofolate reductase
CAS:
54-62-6
Formula:
C19H20N8O5
Molecular Weight:
440.42
Pathway:
Cell Cycle/Checkpoint
Purity:
0.98
SMILES:
Nc1nc(N)c2nc(CNc3ccc(cc3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)cnc2n1
Target:
Antifolate

References

Littlefield, J. W . Selection of Hybrids from Matings of Fibroblasts in vitro and Their Presumed Recombinants[J]. Science, 1964, 145(3633):709-710. Cole, P. D . Phase II Trial of Oral Aminopterin for Adults and Children with Refractory Acute Leukemia[J]. Clinical Cancer Research, 2005, 11(22):8089-8096.