BMP signaling agonist sb4

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TargetMol
Product Code: TAR-T7799
Supplier: TargetMol
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TAR-T7799-5mg5mg£102.00
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TAR-T7799-1mL1 mL * 10 mM (in DMSO)£105.00
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TAR-T7799-10mg10mg£115.00
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TAR-T7799-25mg25mg£143.00
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TAR-T7799-50mg50mg£173.00
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TAR-T7799-100mg100mg£229.00
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TAR-T7799-200mg200mg£309.00
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TAR-T7799-500mg500mg£485.00
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Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
SB 4 is an agonist of benzoxazole bone morphogenetic protein (BMP) signaling (EC50 :74 nM)
CAS:
100874-08-6
Formula:
C14H10BrNOS
Molecular Weight:
320.2
Pathway:
Stem Cells
Purity:
0.9994
SMILES:
Brc1ccc(CSc2nc3ccccc3o2)cc1
Target:
TGF-beta/Smad

References

Bradford S T J , Ranghini E J , Grimley E , et al. High-throughput screens for agonists of bone morphogenetic protein (BMP) signaling identify potent benzoxazole compounds[J]. Journal of Biological Chemistry, 2019. Zhang H, Chen C, Liu Y, et al. NRF-2/HO-1 Pathway-Mediated SHOX2 Activation Is a Key Switch for Heart Rate Acceleration by Yixin-Fumai Granules. Oxidative Medicine and Cellular Longevity. 2022