TargetMol

Quercetagetin

Product Code:
 
TAR-T8114
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T8114-1mg1mg£143.00
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TAR-T8114-5mg5mg£243.00
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TAR-T8114-10mg10mg£326.00
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TAR-T8114-25mg25mg£501.00
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TAR-T8114-50mg50mg£691.00
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TAR-T8114-100mg100mg£938.00
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TAR-T8114-500mg500mg£1,813.00
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Further Information

Bioactivity:
Quercetagetin (6-Hydroxyquercetin) is the major flavonoid isolated from Citrus unshiu. It is a moderately potent and selective, cell-permeable pim-1 kinase inhibitor (IC50: 0.34 μM).
CAS:
90-18-6
Formula:
C15H10O8
Molecular Weight:
318.237
Pathway:
JAK/STAT signaling; Chromatin/Epigenetic
Purity:
0.9965
SMILES:
Oc1ccc(cc1O)-c1oc2cc(O)c(O)c(O)c2c(=O)c1O
Target:
Pim

References

Baek S, et al. Structural and functional analysis of the natural JNK1 inhibitor quercetagetin. J Mol Biol. 2013 Jan 23;425(2):411-23. Yang X, et al. Isolation and identification of an antioxidant flavonoid compound from citrus-processing by-product. J Sci Food Agric. 2011 Aug 15;91(10):1925-7. Holder S, et al. Characterization of a potent and selective small-molecule inhibitor of the PIM1 kinase. Mol Cancer Ther. 2007 Jan;6(1):163-72.