TargetMol

Dihydroberberine

Product Code:
 
TAR-T8189
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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CodeSizePrice
TAR-T8189-1mg1mg£103.00
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TAR-T8189-5mg5mg£148.00
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TAR-T8189-1mL1 mL * 10 mM (in DMSO)£169.00
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TAR-T8189-10mg10mg£209.00
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TAR-T8189-25mg25mg£329.00
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TAR-T8189-50mg50mg£454.00
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TAR-T8189-100mg100mg£623.00
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This product comes from: United States.
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Further Information

Bioactivity:
Dihydroberberine has anti-atherosclerotic, anti-inflammatory, hypolipidemic and antitumor activities. It inhibits human ether-a-go-go-related gene (hERG) channels and remarkably reduces Hsp90 expression and its interaction with hERG.
CAS:
483-15-8
Formula:
C20H19NO4
Molecular Weight:
337.375
Pathway:
JAK/STAT signaling; Angiogenesis; Membrane transporter/Ion channel; Tyrosine Kinase/Adaptors; Metabolism; Cytoskeletal Signaling
Purity:
0.9377
SMILES:
COc1ccc2C=C3N(CCc4cc5OCOc5cc34)Cc2c1OC
Target:
Potassium Channel; HSP; HER

References

Yu D, et al. Inhibitory effects and mechanism of dihydroberberine on hERG channels expressed in HEK293 cells. PLoS One. 2017 Aug 1;12(8):e0181823.