Selpercatinib

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TargetMol
Product Code: TAR-T8222
Supplier: TargetMol
CodeSizePrice
TAR-T8222-2mg2mg£95.00
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TAR-T8222-5mg5mg£108.00
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TAR-T8222-1mL1 mL * 10 mM (in DMSO)£114.00
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TAR-T8222-10mg10mg£135.00
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TAR-T8222-25mg25mg£213.00
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TAR-T8222-50mg50mg£302.00
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TAR-T8222-100mg100mg£497.00
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TAR-T8222-200mg200mg£687.00
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TAR-T8222-500mg500mg£994.00
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Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
Selpercatinib is a tyrosine kinase inhibitor with antineoplastic properties(IC50 of 14.0 nM, 24.1 nM, and 530.7 nM for RET (WT), RET (V804M) , and RET (G810R), respectively)
CAS:
2152628-33-4
Formula:
C29H31N7O3
Molecular Weight:
525.613
Pathway:
Tyrosine Kinase/Adaptors; Apoptosis
Purity:
0.9977
SMILES:
COc1ccc(CN2C3CC2CN(C3)c2ccc(cn2)-c2cc(OCC(C)(C)O)cn3ncc(C#N)c23)cn1
Target:
c-RET

References

Steven W. Andrews, et al. Substituted pyrazolo[1,5-a]pyridine compounds as ret kinase inhibitors. WO2018071447A1.