Lisuride maleate
| Code | Size | Price |
|---|
| TAR-T8775-5mg | 5mg | £571.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Lisuride maleate is an agonist of Dopamine receptor and anti-Parkinson's agent.?Displays high affinity for D2, D3 and D4 receptors along with 5-HT1A.?Exhibits some 5-HT2B receptor antagonist properties.?Decreases prolactin release;?reduces inflammatory mediators such as TNF-α and IL6.?Exhibits anticonvulsive effects.?Acts similar to bromocriptine
CAS:
19875-60-6
Formula:
C20H26N4O.C4H4O4.?H2O
Molecular Weight:
459.02
Purity:
0.98
SMILES:
0
References
Hofmann C , Penner U , Dorow R , et al. Lisuride, a dopamine receptor agonist with 5-HT2B receptor antagonist properties: absence of cardiac valvulopathy adverse drug reaction reports supports the concept of a crucial role for 5-HT2B receptor agonism in cardiac valvular fibrosis.[J]. Clinical Neuropharmacology, 2006, 29(2):80-86.
Zweckberger K , Simunovic F , Kiening K L , et al. Anticonvulsive effects of the dopamine agonist lisuride maleate after experimental traumatic brain injury.[J]. Neuroscience Letters, 2010, 470(2):150-154.
Jiang K, Liu X, Su R. Contrasting effects of DOI and lisuride on impulsive decision-making in delay discounting task. Psychopharmacology. 2022: 1-15.
Zhu H, Liu X, Wang X, et al.G?? subunit inhibitor decreases DOM-induced head twitch response via the PLC?/IP3/Ca2+/ERK and cAMP signaling pathways.European Journal of Pharmacology.2023: 176038.