Amorolfine HCL
| Code | Size | Price |
|---|
| TAR-T8812-1mL | 1 mL * 10 mM (in DMSO) | £111.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
| TAR-T8812-5mg | 5mg | £111.00 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Quantity:
Prices exclude any Taxes / VAT
Overview
Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃
Documents
Further Information
Bioactivity:
Amorolfine HCL is an antifungal reagent. It exerts the antifungal activity by selectively interrupting two steps in the pathway of ergosterol synthesis and eventually disrupting the function and structure of fungal cell membrane. Amorolfine, a morpholine antifungal drug, can inhibit D14 reductase and D7-D8 isomerase. These enzymes can deplete ergosterol and cause ignosterol to accumulate in the fungal cytoplasmic cell membranes.
CAS:
106614-68-0
Formula:
C21H36ClNO
Molecular Weight:
353.98
Pathway:
Microbiology/Virology
Purity:
0.98
SMILES:
Cl.CCC(C)(C)c1ccc(CC(C)CN2CC(C)OC(C)C2)cc1
Target:
Antibiotic
References
Espinel-Ingroff A, et al. Antimicrob Agents ChemOthers. 1984 Jul; 26(1):5-9.
Polak, A., Preclinical data and mode of action of amorolfine. Dermatology, 1992. 184 Suppl 1: p. 3-7.