Niraparib tosylate monohyrate

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TargetMol
Product Code: TAR-T9497
Supplier: TargetMol
CodeSizePrice
TAR-T9497-5mg5mg£115.00
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Quantity:
TAR-T9497-1mL1 mL * 10 mM (in DMSO)£127.00
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Quantity:
TAR-T9497-10mg10mg£134.00
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Quantity:
TAR-T9497-25mg25mg£166.00
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Quantity:
TAR-T9497-50mg50mg£189.00
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Quantity:
TAR-T9497-100mg100mg£254.00
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Quantity:
TAR-T9497-200mg200mg£346.00
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Quantity:
TAR-T9497-500mg500mg£531.00
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Quantity:
Prices exclude any Taxes / VAT

Overview

Regulatory Status: RUO
Shipping:
cool pack
Storage:
-20℃

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Documents

Further Information

Bioactivity:
Niraparib, also know as MK-4827, is an inhibitor of poly (ADP-ribose) polymerase (PARP) with potential antineoplastic activity. MK4827 inhibits PARP activity, enhancing the accumulation of DNA strand breaks and promoting genomic instability and apoptosis. The PARP family of proteins detect and repair single strand DNA breaks by the base-excision repair (BER) pathway.
CAS:
1613220-15-7
Formula:
C26H28N4O4S
Molecular Weight:
492.59
Pathway:
DNA Damage/DNA Repair; Chromatin/Epigenetic
Purity:
0.9962
SMILES:
O=S(C1=CC=C(C)C=C1)(O)=O.O=C(C2=CC=CC3=CN(C4=CC=C([C@H]5CNCCC5)C=C4)N=C23)N
Target:
PARP